The Fashion Design & Cosmetology Department at Matili TTI, led by Florence Lodi, nurtures creative fashion design and cosmetology expertise, promoting personal care skills and artistic innovation.

The Electrical & Electronics Engineering Department, led by Don Adongo, provides cutting-edge training in electrical systems, electronics, and renewable energy technologies, fostering engineering innovation.

The Computing & Informatics Department, led by Metrine Onala, equips students with modern IT skills, software development expertise, and robust e-learning platforms for cutting-edge tech careers.

The Business Studies & Entrepreneurship Department, led by Abigael Makanga, fosters skills in management, accounting, and entrepreneurial ventures for leadership and innovation in business.

The Building & Civil Engineering Department, led by Robert Mojo, trains students in modern construction techniques, surveying, and sustainable building practices.

The Agriculture & Environmental Studies Department, led by Makari Margret, focuses on sustainable farming, environmental conservation, and agribusiness, fostering eco-friendly practices.

The Hospitality & Tourism Management Department, led by Mildred Wasike, prepares students for careers in food and beverage, tourism, and hotel management, promoting service excellence.

The Liberal Studies Department, led by Julius Mong'are, offers courses in social sciences and community development to foster well-rounded professionals and promote social development.

The Mathematics & Applied Sciences Department, led by Mr. Kituyi Manasseh, provides foundational training in laboratory sciences and health technology, fostering scientific innovation.

The Mechanical and Automotive Engineering Department, led by Moses Simiyu, is a center of excellence, offering training in CNC machining, automotive repair, and mechanical systems.